Intrapleural Fibrinolytics

Timeline Drug constitution Action
0 hours Mix 10mg Alteplase with the solute provided, and dilute with 30 mls of saline/water. Administer this through the chest drain Clamp the tube after administartion
1 hour Unclamp the drain and allow free drainage
2 hours Mix 5 mg Dornase Alpha with 30 mls of sterile water or saline. Administer through the drain Clamp the tube after administeration
3 hours Unclamp the drain and allow free drainage
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